A(n)
facilitates or mimics the activity of a given neurotransmitter system.
Cocaine has two effects on synaptic transmission: it impairs the reuptake of dopamine and it causes more dopamine to be released into the synapse. Based on this description, how would cocaine be classified--agonist, antagonist, or reuptake inhibitor? Why?
Drugs such as lidocaine and novocaine act as Na+ channel blockers. In other words, they prevent sodium from moving across the neuronal membrane. Why would this particular effect make these drugs such effective local anesthetics?
Box 1: Select the best answer
agonist
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